Prescription: Murder

In Columbo's first outing, a psychiatrist uses a patient he is having an affair with to help him kill his wife, but his perfect alibi may come apart at the hands of a seemingly befuddled LAPD lieutenant.

• 
  Richard Irving
• 
  George Bisk

• 
  Peter Falk
  Columbo
• 
  Gene Barry
  Dr. Ray Flemming
• 
  Katherine Justice
  Joan Hudson
• 
  William Windom
  Burt Gordon
• 
  Nina Foch
  Carol Flemming
• 
  Virginia Gregg
  Miss Petrie
• 
  Andrea King
  Cynthia Gordon
• 
  Susanne Benton
  The Blonde
• 
  Ena Hartman
  Nurse
• 
  Sherry Boucher
  Air Hostess
• 
  Anthony James
  Tommy
• 
  Frank Baker
  Man in Park (uncredited)
• 
  Jim Creech
  Policeman in Hospital (uncredited)
• 
  Ed Haskett
  Party Guest (uncredited)
• 
  Clark Howat
  Doctor (uncredited)
• 
  Mark Russell
  Policeman (uncredited)
• 
  Don Stewart
  Airline Ticket Man (uncredited)
• 
  Tom Williams
  Laundry Delivery Man (uncredited)